Master thesis application development virus
Viral Immune Modulation
master thesis Herpesviruses are extremely complex viruses. We are just beginning to understand exactly how these pathogens manipulate our immune system to establish chronic infections.
In order to develop new therapies and vaccines, it is first necessary to understand the interplay between herpesviruses and their hosts. In addition, our research analyzes how these viruses so successfully establish chronic infections. The question of how herpesviruses circumvent or weaken the defensive line of our innate immune system plays a central role, as this is application development virus requirement for master thesis application development virus viruses to successfully establish lifelong infection.
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Via master thesis of years of coevolution, herpesviruses have adapted application development virus perfectly to their hosts. They know exactly which switches to pull to weaken certain aspects master thesis application development virus the immune response as well as to enhance responses that benefit them.
One goal of the master thesis application development virus group is to identify novel viral proteins that are directly involved in manipulation of immune defenses. These proteins are potential targets for the development of new antiviral therapies.
CMV is a common pathogen, thought master thesis application development virus infect half of the European population. In many healthy individuals, CMV infection is unrecognized - it may cause mild illness or even be completely asymptomatic. In addition, although it is not always common knowledge, CMV is the most common viral cause of birth defects.
Infection of the mother during pregnancy can lead to infection of master thesis application development here fetus, resulting in permanent damage observed at birth or later in childhood. In fact, CMV infection during pregnancy is the more info common cause of non-genetic deafness in children. To date, there is no vaccine against Link and there is only a limited selection of antiviral drugs available, which are unfortunately accompanied by serious side effects.
KSHV was first discovered in Since master thesis, it has been identified as the causative agent of application development virus least three types of cancer: The goal of our research activities is to gain novel insights into the interplay between the herpesviruses CMV and KSHV and master thesis application development virus hosts, and thus better understand how these viruses cause illness.
Development virus insights are master thesis application foundation required to develop innovative, specific therapies against herpesviruses.
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Here you can find a complete list development virus publications. During his or her lifetime, master thesis application human being is infected with at least one of the nine human herpesviruses. In most cases, the immune system of healthy people keeps the infection under control and severe master thesis application development virus only rarely develops. Herpesviruses have adapted excellently to their host — development virus manipulate the immune system in many different ways and manage to remain in the host application development virus.
Herpesviruses have coexisted with humans for millions of years, and during this time they have developed application development virus strategies to escape immune system control.
An important representative of the herpesvirus family is cytomegalovirus CMV — about half of the German population carries this virus.
Pathogens entering our body only remain unnoticed for a short period.
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Within minutes our immune cells detect the invader and trigger an immune response. Instantly, the immune system initiates the process of fighting off the infection. This initial protective mechanism is very fast because it focuses on recognition of master thesis application development virus structural properties — in this case bacterial or viral Application development virus.
Understanding the tricks and survival strategies of viruses to effectively combat them:
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Domestic animals are the primary source of animal-to-human transmission of influenza viruses and avian influenza is a major problem in poultry farming. For both of these reasons, influenza viruses in animals are closely monitored.
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Treatment of HIV infection is based on combinations of antiviral drugs. To identify the optimal drug combination for each patient, we develop computational methods based on the genetic composition of the virus population of the patient. For any given therapy, we predict the probability that the virus will develop escape mutations that would result in drug resistance and eventually in treatment failure.
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